St. Petersburg’s LETI Electrotechnical University is developing an express diagnostics system and therapy for COVID-19.
Researchers at St. Petersburg’s LETI Electrotechnical University suggest using peptides to diagnose and treat COVID-19, a spokesperson for the University told Saint-Petersburg TV Channel.
Peptides, short chains of amino acid residues, are spatially complementary to the COVID-19 spikes. The virus uses these spikes to get attached to cells in lungs and other organs by using their ACE-2 receptors. Having attached itself to a cell, the virus penetrates into it and uses it to reproduce itself.
LETI researchers believe that to inactivate coronavirus, oligopeptide molecules can be used. These molecules can detect COVID-19 and prevent it from attaching to cell receptors.
The researchers will have to develop peptide sequences and a platform for a biochip to transport oligopeptide molecules, and test the method. The entire cycle is expected to take 8 to 10 months.